
The genetic code is the set of rules by which information encoded in
genetic material (DNA or
RNA sequences) is translated into proteins (amino acid sequences) by living cells.
Specifically, the code defines a mapping between tri-nucleotide
sequences called codons and amino acids; every triplet of nucleotides in
a nucleic acid sequence specifies a single amino acid.
Each protein-coding in the DNA is transcribed into a template molecule, known as messenger RNA or mRNA. This in turn is translated on the ribosome into an amino acid chain or
polypeptide. The process of translation requires transfer RNAs specific
for individual amino acids with the amino acids covalently attached to
them. Some transfer RNAs do not have an amino acid counterpart. When a codon for such a transfer RNA is read, the translation stops.
Almost all living creatures use the same genetic code. The table below is based on the standard version. (U stands for Uracil in RNA; in DNA this would be a T for Thymine).
| 2e base | |||||
|---|---|---|---|---|---|
| U | C | A | G | ||
| 1e base | U |
UUU Phenylalanine UUC Phenylalanine UUA Leucine UUG Leucine |
UCU Serine UCC Serine UCA Serine UCG Serine |
UAU Tyrosine UAC Tyrosine UAA Stop UAG Stop |
UGU Cysteine UGC Cysteine UGA Stop UGG Tryptophan |
| C |
CUU Leucine CUC Leucine CUA Leucine CUG Leucine |
CCU Proline CCC Proline CCA Proline CCG Proline |
CAU Histidine CAC Histidine CAA Glutamine CAG Glutamine |
CGU Arginine CGC Arginine CGA Arginine CGG Arginine |
|
| A |
AUU Isoleucine AUC Isoleucine AUA Isoleucine AUG Methionine1 |
ACU Threonine ACC Threonine ACA Threonine ACG Threonine |
AAU Asparagine AAC Asparagine AAA Lysine AAG Lysine |
AGU Serine AGC Serine AGA Arginine AGG Arginine |
|
| G |
GUU Valine GUC Valine GUA Valine GUG Valine |
GCU Alanine GCC Alanine GCA Alanine GCG Alanine |
GAU Aspartate GAC Aspartate GAA Glutamate GAG Glutamate |
GGU Glycine GGC Glycine GGA Glycine GGG Glycine |
|
1 The AUG codon codes for methionine and serves as a starting point. The first AUG in mRNA marks the starting point for translation.